Answer: Dead Space

The Dead Space gaming franchise is a horror/survival themed third-person space adventure starring Ship Systems Engineer turned survivalist, Isaac Clarke.

In a nod to the hard Science Fiction genre that preceded the franchise, developers named their protagonist after acclaimed 20th century Sci-Fi writers Isaac Asimov and Arthur C. Clarke.

Isaac Clarke certainly isn’t the only space-faring video game character to lift his name from a real person. Commander Shepard, of the Mass Effect game franchise, is named after American Astronaut Alan Shepard.