I can type fairly fast...
I use a ton of built-in shortcut keys, although the majority of the shortcuts I use the most are customized using autohotkey, like these:
Alt+E = Launchy
Alt+J = Show/Hide Firefox
Win+C = Show/Hide SecureCRT (ssh)
Alt+O = Show/Hide Pidgin
Alt+P = Switch focus to Pidgin message window
Alt+M = Show/Hide email client
Alt+D = Show/Hide delicious bookmarks list
Win+Alt+H = Hide all windows but the current one
Win+G = Go to next unread item in Google Reader
Win+A = Show/Hide note-taking application
Alt+T = Show/Hide todo list application ( Tudumo )
Win+Tab = Switcher (replacement for flip3d)
... there's more, but I won't list them all
I should write up the most useful shortcut keys from a time-saving perspective. Some tasks are better using the mouse, some are better using the keyboard.