First search the REGISTRY for the complete string. Also look to see if hidden files or sub-folders are in those folders. I think some are required for installed programs, might use them as scratch area's and IF not there, those apps might not run OR just recreate them?
I've got quite a few too... some of them (note some are files with sizes) :
================
C:\>dir {* /s /p
Volume in drive C is OS
Volume Serial Number is 1C5C-DD5E
Directory of C:\
09/01/11 01:31 PM 2,456 {BB9EE6CC-D939-45DF-B7D1-5E1E7E0BB592}
1 File(s) 2,456 bytes
Directory of C:\Program Files\Common Files\Logishrd\CacheMSI
08/13/10 10:00 AM <DIR> {987FE247-4E69-4A2E-A961-D14F901FDBF6}
0 File(s) 0 bytes
Directory of C:\Program Files (x86)\Adobe\Reader 11.0\Setup Files
01/20/13 11:48 AM <DIR> {AC76BA86-7AD7-1033-7B44-AB0000000001}
0 File(s) 0 bytes
Directory of C:\Program Files (x86)\Google\Update\Download
02/15/13 04:30 AM <DIR> {430FD4D0-B729-4F61-AA34-91526481799D}
02/22/13 10:48 PM <DIR> {4DC8B4CA-1BDA-483E-B5FA-D3C12E15B62D}
11/19/11 01:06 PM <DIR> {74AF07D8-FB8F-4D51-8AC7-927721D56EBB}
12/15/11 04:06 AM <DIR> {8A69D345-D564-463C-AFF1-A69D9E530F96}
02/21/13 08:42 PM <DIR> {8BA986DA-5100-405E-AA35-86F34A02ACBF}
04/29/11 03:37 PM <DIR> {E845EB6B-5ADF-4EFC-88FF-EC095F12BCAF}
0 File(s) 0 bytes
Directory of C:\Program Files (x86)\HP\cio
02/22/11 10:39 AM <DIR> {C788B026-20BD-4E96-B698-533F1D6C5013}
0 File(s) 0 bytes
Directory of C:\Program Files (x86)\HP\Digital Imaging
01/06/13 08:19 AM <DIR> {131D8ED6-4864-4554-9BAB-09B47C232522}
01/06/13 08:10 AM <DIR> {4E484899-4F93-4086-88BA-56BDDF47A776}
0 File(s) 0 bytes
Directory of C:\Program Files (x86)\HP\Temp
01/06/13 08:19 AM <DIR> {131D8ED6-4864-4554-9BAB-09B47C232522}
02/29/12 02:49 PM <DIR> {4E484899-4F93-4086-88BA-56BDDF47A776}
0 File(s) 0 bytes
Directory of C:\Program Files (x86)\InstallShield Installation Information
12/30/12 11:43 AM <DIR> {0F86FD09-BA63-4E45-A70B-604C1106C2F2}
01/01/13 10:17 AM <DIR> {2FBA0453-1A7F-4AAB-93E7-81FBD2CF41C9}
02/20/11 04:36 PM <DIR> {32821558-2C36-4FD0-A891-CA65360B0EC7}
.
.
.
Total Files Listed:
8263 File(s) 3,049,813,385 bytes
851 Dir(s) 45,958,873,088 bytes free
=====================
I am NOT about to mess with them at all...
Irv S.
Irv S.