Although I am not a Keyboard Ninja I still like to navigate quickly through Windows.  You can make your mousing more efficient using the snap to option which is inherent to XP.  This also works with Vista although getting to this setting is obviously different.

Start Settings Control Panel and double click the Mouse icon.  Then in Mouse Properties go to Pointer Options.  Place a check in the Snap To section next to “Automatically move pointer to …”  Click Apply and Ok and you’re done.

Because this will send the pointer to a default button in a dialog box every time you may want to use caution if you’re click happy.  What are some of the ways you make mousing more efficient on your systems?